CATIONIC LIPID FOR NUCLEIC ACID DELIVERY
An object of the present invention is to provide a cationic lipid capable of achieving higher intracellular delivery efficiency than conventional cationic lipids, when used as a lipid membrane structure which is a carrier for delivering functional nucleic acid. A cationic lipid represented by the fo...
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| Main Authors | , , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
25.02.2016
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| Subjects | |
| Online Access | Get full text |
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| Abstract | An object of the present invention is to provide a cationic lipid capable of achieving higher intracellular delivery efficiency than conventional cationic lipids, when used as a lipid membrane structure which is a carrier for delivering functional nucleic acid. A cationic lipid represented by the formula (1): (see formula 1) wherein each symbol is as defined in the present DESCRIPTION.
La présente invention concerne un lipide cationique qui, lorsqu'il est utilisé sous la forme d'une structure de membrane lipidique laquelle est un support pour l'administration d'acide nucléique fonctionnel, permet d'obtenir une plus grande efficacité d'administration intracellulaire qu'avec un lipide cationique classique. Le lipide cationique est représenté par la formule (1). (Dans la formule, chaque symbole est tel que défini dans la présente description.) |
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| AbstractList | An object of the present invention is to provide a cationic lipid capable of achieving higher intracellular delivery efficiency than conventional cationic lipids, when used as a lipid membrane structure which is a carrier for delivering functional nucleic acid. A cationic lipid represented by the formula (1): (see formula 1) wherein each symbol is as defined in the present DESCRIPTION.
La présente invention concerne un lipide cationique qui, lorsqu'il est utilisé sous la forme d'une structure de membrane lipidique laquelle est un support pour l'administration d'acide nucléique fonctionnel, permet d'obtenir une plus grande efficacité d'administration intracellulaire qu'avec un lipide cationique classique. Le lipide cationique est représenté par la formule (1). (Dans la formule, chaque symbole est tel que défini dans la présente description.) |
| Author | HARASHIMA, HIDEYOSHI KUBO, KAZUHIRO TANGE, KOTA OTA, MASAKI NOGUCHI, YUKI NAKAI, YUTA AKITA, HIDETAKA SASAKI, SHOTA HATAKEYAMA, HIROTO SHIMIZU, NAYUTA |
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| DocumentTitleAlternate | LIPIDE CATIONIQUE DESTINE A L'ADMINISTRATION D'ACIDES NUCLEIQUES |
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| Notes | Application Number: CA20152958542 |
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| RelatedCompanies | NOF CORPORATION NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY |
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| Snippet | An object of the present invention is to provide a cationic lipid capable of achieving higher intracellular delivery efficiency than conventional cationic... |
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| Title | CATIONIC LIPID FOR NUCLEIC ACID DELIVERY |
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