LENTIVIRAL VECTORS
This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin- neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors...
Saved in:
Main Authors | , , , , , , , , , , |
---|---|
Format | Patent |
Language | English French |
Published |
28.02.2023
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin- neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).
L'invention concerne des vecteurs de transfert de gènes lentiviraux pseudotypés avec des protéiens d'hémagglutinine-neuraminidase (HN) et de fusion (F) à partir d'un paramyxovirus respiratoire, comprenant un promoteur et un transgène; ainsi que leurs procédés de fabrication. La présente invention concerne également l'utilisation desdits vecteurs en thérapie génique, notamment pour le traitement de maladies des voies respiratoires telles que la fibrose kystique (CF) |
---|---|
AbstractList | This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin- neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).
L'invention concerne des vecteurs de transfert de gènes lentiviraux pseudotypés avec des protéiens d'hémagglutinine-neuraminidase (HN) et de fusion (F) à partir d'un paramyxovirus respiratoire, comprenant un promoteur et un transgène; ainsi que leurs procédés de fabrication. La présente invention concerne également l'utilisation desdits vecteurs en thérapie génique, notamment pour le traitement de maladies des voies respiratoires telles que la fibrose kystique (CF) |
Author | GRIESENBACH, UTA DAVIES, LEE ADRIAN PAUL-SMITH, MICHAEL CHRISTIAN PRINGLE, IAN ANDREW BOYD, ALAN CHRISTOPHER MCLACHLAN, GERARD PYTEL, KAMILA MALGORZATA GILL, DEBORAH REBECCA ALTON, ERIC WALTER FREDERICK WOLFGANG HYDE, STEPHEN CHARLES INOUE, MAKOTO |
Author_xml | – fullname: INOUE, MAKOTO – fullname: MCLACHLAN, GERARD – fullname: GRIESENBACH, UTA – fullname: PRINGLE, IAN ANDREW – fullname: ALTON, ERIC WALTER FREDERICK WOLFGANG – fullname: PYTEL, KAMILA MALGORZATA – fullname: GILL, DEBORAH REBECCA – fullname: HYDE, STEPHEN CHARLES – fullname: PAUL-SMITH, MICHAEL CHRISTIAN – fullname: DAVIES, LEE ADRIAN – fullname: BOYD, ALAN CHRISTOPHER |
BookMark | eNrjYmDJy89L5WQQ8nH1C_EM8wxy9FEIc3UO8Q8K5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c6ORpYm5oZGps7GhFUAAJbTHxk |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | VECTEURS LENTIVIRAUX |
ExternalDocumentID | CA2947125C |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_CA2947125C3 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 14:23:45 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_CA2947125C3 |
Notes | Application Number: CA20152947125 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230228&DB=EPODOC&CC=CA&NR=2947125C |
ParticipantIDs | epo_espacenet_CA2947125C |
PublicationCentury | 2000 |
PublicationDate | 20230228 |
PublicationDateYYYYMMDD | 2023-02-28 |
PublicationDate_xml | – month: 02 year: 2023 text: 20230228 day: 28 |
PublicationDecade | 2020 |
PublicationYear | 2023 |
RelatedCompanies | ID PHARMA CO., LTD IMPERIAL INNOVATIONS LIMITED |
RelatedCompanies_xml | – name: IMPERIAL INNOVATIONS LIMITED – name: ID PHARMA CO., LTD |
Score | 3.452 |
Snippet | This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin- neuraminidase (HN) and fusion (F) proteins from a respiratory... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
Title | LENTIVIRAL VECTORS |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230228&DB=EPODOC&locale=&CC=CA&NR=2947125C |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQSTQ2MTYxBy0rNzM20QXWeMm6lhZmKbppaaZJSYZG5sAcBdo77Otn5hFq4hVhGsHEkAHbCwM-J7QcfDgiMEclA_N7Cbi8LkAMYrmA11YW6ydlAoXy7d1CbF3UoL1jYHvayMhCzcXJ1jXA38XfWc3Z2dbZUc0vyNbIElgKG5k6MzOwghrRoFP2XcOcQHtSCpArFDdBBrYAoFl5JUIMTKl5wgyczrB714QZOHyh091AJjTnFYswCPm4-oV4hnkGOfoohLk6h_gHBYsyyLu5hjh76AINj4f7I97ZEeYKYzEGFmDvPlWCQcEsKc04ycQ0LTktxdTEODHZwjg5GXQKW5qFgUmaqVmqJIMELlOkcEtJM3CBQgOy91qGgaWkqDRVFlh7liTJgT0OABXFcXw |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3NT4MwFH-Z0zhvbmrm53Yw3IhKy8cOxLACAeVjQSS7kdHRzMtcHMZ_3xZBvezWtMlL-5Lf-2jf7xXgdoEwwrooK9cQlrnHo_LE0JYyY2pRPCg6R5TgDoeR5r3ip7k678Cq5cLUfUK_6uaIHFGU472q7fXm7xLLrmsrt3fFG596f3RT05aa7JjH04piSPbUdGaxHROJEJNYUpSYyoRbYUUle7Cvi968InDKpoKTsvnvUNxjOJhxWeuqD51yPYAeaf9dG8Bh2Dx382GDvO0J9AMnSv3MT6xgnDkkjZOXUxi5Tko8mQvPf8-RE6vdBTqDLs_uyyGMtYKhAquMsqWK0YIaiFLRhY0Z95ipWnkOw11SLnYvjaDnpWGQB370fAlHQjM_POwr6FYfn-U196RVcVMr4RuLvHRp |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=LENTIVIRAL+VECTORS&rft.inventor=INOUE%2C+MAKOTO&rft.inventor=MCLACHLAN%2C+GERARD&rft.inventor=GRIESENBACH%2C+UTA&rft.inventor=PRINGLE%2C+IAN+ANDREW&rft.inventor=ALTON%2C+ERIC+WALTER+FREDERICK+WOLFGANG&rft.inventor=PYTEL%2C+KAMILA+MALGORZATA&rft.inventor=GILL%2C+DEBORAH+REBECCA&rft.inventor=HYDE%2C+STEPHEN+CHARLES&rft.inventor=PAUL-SMITH%2C+MICHAEL+CHRISTIAN&rft.inventor=DAVIES%2C+LEE+ADRIAN&rft.inventor=BOYD%2C+ALAN+CHRISTOPHER&rft.date=2023-02-28&rft.externalDBID=C&rft.externalDocID=CA2947125C |