METHODS AND KITS FOR IDENTIFYING PRE-CANCEROUS COLORECTAL POLYPS AND COLORECTAL CANCER

• Main Authors: MOSHAYOFF, VARDIT, COHEN, DANA, FAKTOR, OURIEL
• Format: Patent
• Language: English; French
• Published: 15.10.2015
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

The present invention relates, according to some embodiments, to methods and kits for identifying a subject having pre-cancerous advanced polyps or colorectal cancer based on the expression profile(s) of specific m RNA biomarkers. The present invention further comprises methods and kits for diagnosing, preventing, managing therapy, monitoring and identifying predisposition to colorectal cancer. La présente invention concerne, selon certains modes de réalisation, des procédés et des kits d'identification d'un sujet affecté de polypes avancés précancéreux ou d'un cancer colorectal d'après le ou les profils d'expression de biomarqueurs d'ARNm spécifiques. La présente invention concerne en outre des procédés et des kits permettant le diagnostic, la prévention, la gestion de la thérapie, le suivi et l'identification d'une prédisposition à un cancer colorectal.