SUBSTITUTED PYRIDO[3,2-B]INDOYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF AS ANTICANCER AGENTS

The present invention is directed to substituted pyrido[3,2-b ]indoyl compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions as anticancer agents. In particular, the present invention provides a compound of the formula (II). L...

Full description

Saved in:
Bibliographic Details
Main Authors DEGNAN, ANDREW P, DEBENEDETTO, MIKKEL V, GAVAI, ASHVINIKUMAR V, SCHMITZ, WILLIAM D, VACCARO, WAYNE, LEE, FRANCIS Y, HILL, MATTHEW D, HAN, WENING, MANDAL, SUNIL KUMAR, HUANG, HONG, QUESNELLE, CLAUDE A, GILL, PATRICE, NORRIS, DEREK J, STARRETT, JOHN E., JR, O'MALLEY, DANIEL, DELUCCA, GEORGE V, TOKARSKI, JOHN S, FANG, HAIQUAN
Format Patent
LanguageEnglish
French
Published 02.07.2015
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

Abstract The present invention is directed to substituted pyrido[3,2-b ]indoyl compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions as anticancer agents. In particular, the present invention provides a compound of the formula (II). La présente invention concerne des composés de pyrido[3,2-b]indoyl substitués, des compositions acceptables sur le plan pharmaceutique comprenant les composés de l'invention et des méthodes d'utilisation de ces compositions comme agents anticancéreux. Plus précisément, la présente invention concerne un composé de formule (II).
AbstractList The present invention is directed to substituted pyrido[3,2-b ]indoyl compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions as anticancer agents. In particular, the present invention provides a compound of the formula (II). La présente invention concerne des composés de pyrido[3,2-b]indoyl substitués, des compositions acceptables sur le plan pharmaceutique comprenant les composés de l'invention et des méthodes d'utilisation de ces compositions comme agents anticancéreux. Plus précisément, la présente invention concerne un composé de formule (II).
Author SCHMITZ, WILLIAM D
TOKARSKI, JOHN S
FANG, HAIQUAN
HUANG, HONG
NORRIS, DEREK J
DEBENEDETTO, MIKKEL V
QUESNELLE, CLAUDE A
STARRETT, JOHN E., JR
DEGNAN, ANDREW P
GAVAI, ASHVINIKUMAR V
LEE, FRANCIS Y
O'MALLEY, DANIEL
DELUCCA, GEORGE V
HAN, WENING
HILL, MATTHEW D
GILL, PATRICE
VACCARO, WAYNE
MANDAL, SUNIL KUMAR
Author_xml – fullname: DEGNAN, ANDREW P
– fullname: DEBENEDETTO, MIKKEL V
– fullname: GAVAI, ASHVINIKUMAR V
– fullname: SCHMITZ, WILLIAM D
– fullname: VACCARO, WAYNE
– fullname: LEE, FRANCIS Y
– fullname: HILL, MATTHEW D
– fullname: HAN, WENING
– fullname: MANDAL, SUNIL KUMAR
– fullname: HUANG, HONG
– fullname: QUESNELLE, CLAUDE A
– fullname: GILL, PATRICE
– fullname: NORRIS, DEREK J
– fullname: STARRETT, JOHN E., JR
– fullname: O'MALLEY, DANIEL
– fullname: DELUCCA, GEORGE V
– fullname: TOKARSKI, JOHN S
– fullname: FANG, HAIQUAN
BookMark eNqNyr0OgjAUQOEOOvj3DvcBZNDqwHhpizSRlrS3AzGGEFMmAyT4_lESHsDpDOfbslU_9HHDOh8yT5oCKQlV7bS0D348J9lTG2nrOwhbVjYY6QHNTxToShQqkBa4TK9JW-OBCuWUzQFnOn8jlAO8KUN-z9Zd-57iYemOQa5IFEkchyZOY_uKffw0As8pv6RXjif-B_kC-q025Q
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate COMPOSES DE PYRIDO[3,2-B]INDOLE SUBSTITUES ET COMPOSITIONS PHARMACEUTIQUES COMME AGENTS ANTICANCER
ExternalDocumentID CA2934953A1
GroupedDBID EVB
ID FETCH-epo_espacenet_CA2934953A13
IEDL.DBID EVB
IngestDate Fri Jul 19 14:22:33 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_CA2934953A13
Notes Application Number: CA20142934953
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150702&DB=EPODOC&CC=CA&NR=2934953A1
ParticipantIDs epo_espacenet_CA2934953A1
PublicationCentury 2000
PublicationDate 20150702
PublicationDateYYYYMMDD 2015-07-02
PublicationDate_xml – month: 07
  year: 2015
  text: 20150702
  day: 02
PublicationDecade 2010
PublicationYear 2015
RelatedCompanies BRISTOL-MYERS SQUIBB COMPANY
RelatedCompanies_xml – name: BRISTOL-MYERS SQUIBB COMPANY
Score 2.996517
Snippet The present invention is directed to substituted pyrido[3,2-b ]indoyl compounds, pharmaceutically acceptable compositions comprising compounds of the invention...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title SUBSTITUTED PYRIDO[3,2-B]INDOYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF AS ANTICANCER AGENTS
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20150702&DB=EPODOC&locale=&CC=CA&NR=2934953A1
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfR1NS8MwNIwp6k2n4uYHOUhPFrvv9VAkTVJbcW3ph2yIjLZLYJduuIp_3yRu04veQt7jkTx4X3kfAeA2Z715Pu-beiZ8B703Mgo9M5ipM7MYZrxo8yxTVb7-wE17T5P-pAYW214YNSf0Uw1HFBJVCHmvlL5e_TxiEVVbub7PF2Jr-eAkFtE20bH0boyORmyLhgEJsIaxhZHmR5awarKSEolAaU960XLMPn2xZVPK6rdFcY7BfiiIldUJqLGyAQ7x9uO1BjgYb_LdYrkRvfUp4HFqx4mXpELVwHAaeSR47d51dPvN80kwfYY4GIdB6pMYIl9guCgaI0zTRA48-AbGnuoZholLIxo4EElUCfcxjSB6pH4SnwHo0AS7ujjwbMecGUa7q3XPQb1cluwCQF7kI54L92MgM59F12zzNh_OZa6amcw0mqD5J5nWP7BLcCS5rOpVO1egXr1_sGthlav8RvHzC59Mii4
link.rule.ids 230,309,786,891,25594,76903
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfR1NS8MwNIwpzptOxfmZg_RksfteD0XStLXVNS1tKhsio-1S2KUbruLfN4lzetFbyHs8kgfvK-8jANxkrDfP5n1dTbnvoPZGWq6mGtNVpufDtMjbRZrKKl8ycJPe46Q_qYHFdy-MnBP6IYcjconKubxXUl-vfh6xLFlbub7LFnxree9Qw1I20bHwbrSOYpmGHQZWgBWMDYwUEhncqolKSsQDpZ0hjwhlpPRsiqaU1W-L4hyA3ZATK6tDUGNlEzTw98drTbDnb_LdfLkRvfURKOLEjKlHE65qYDiNPCt46d52VPPVI1YwHUMc-GGQECuGiHAMF0U-wnZCxcCDL2DsyZ5hSF07sgMHIoEq4ATbEUQPNqHxMYCOTbGr8gPPtsyZYbS9WvcE1MtlyU4BLPJsVGTc_RiIzGfe1dtFuxjORa6a6UzXWqD1J5mzf2DXoOFSfzwbe-TpHOwLjsva1c4FqFdv7-ySW-gqu5K8_QQ6rY0Y
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=SUBSTITUTED+PYRIDO%5B3%2C2-B%5DINDOYL+COMPOUNDS+AND+PHARMACEUTICAL+COMPOSITIONS+THEREOF+AS+ANTICANCER+AGENTS&rft.inventor=DEGNAN%2C+ANDREW+P&rft.inventor=DEBENEDETTO%2C+MIKKEL+V&rft.inventor=GAVAI%2C+ASHVINIKUMAR+V&rft.inventor=SCHMITZ%2C+WILLIAM+D&rft.inventor=VACCARO%2C+WAYNE&rft.inventor=LEE%2C+FRANCIS+Y&rft.inventor=HILL%2C+MATTHEW+D&rft.inventor=HAN%2C+WENING&rft.inventor=MANDAL%2C+SUNIL+KUMAR&rft.inventor=HUANG%2C+HONG&rft.inventor=QUESNELLE%2C+CLAUDE+A&rft.inventor=GILL%2C+PATRICE&rft.inventor=NORRIS%2C+DEREK+J&rft.inventor=STARRETT%2C+JOHN+E.%2C+JR&rft.inventor=O%27MALLEY%2C+DANIEL&rft.inventor=DELUCCA%2C+GEORGE+V&rft.inventor=TOKARSKI%2C+JOHN+S&rft.inventor=FANG%2C+HAIQUAN&rft.date=2015-07-02&rft.externalDBID=A1&rft.externalDocID=CA2934953A1