SUBSTITUTED PYRIDO[3,2-B]INDOYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF AS ANTICANCER AGENTS

• Main Authors: DEGNAN, ANDREW P, DEBENEDETTO, MIKKEL V, GAVAI, ASHVINIKUMAR V, SCHMITZ, WILLIAM D, VACCARO, WAYNE, LEE, FRANCIS Y, HILL, MATTHEW D, HAN, WENING, MANDAL, SUNIL KUMAR, HUANG, HONG, QUESNELLE, CLAUDE A, GILL, PATRICE, NORRIS, DEREK J, STARRETT, JOHN E., JR, O'MALLEY, DANIEL, DELUCCA, GEORGE V, TOKARSKI, JOHN S, FANG, HAIQUAN
• Format: Patent
• Language: English; French
• Published: 02.07.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention is directed to substituted pyrido[3,2-b ]indoyl compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions as anticancer agents. In particular, the present invention provides a compound of the formula (II). La présente invention concerne des composés de pyrido[3,2-b]indoyl substitués, des compositions acceptables sur le plan pharmaceutique comprenant les composés de l'invention et des méthodes d'utilisation de ces compositions comme agents anticancéreux. Plus précisément, la présente invention concerne un composé de formule (II).