FLUORO-[1,3]OXAZINES AS BACE1 INHIBITORS

The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic...

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Main Authors GUBA, WOLFGANG, WOLTERING, THOMAS, PINARD, EMMANUEL, HILPERT, HANS, OBST SANDER, ULRIKE, KUGLSTATTER, ANDREAS, WOSTL, WOLFGANG, LIMBERG, ANJA
Format Patent
LanguageEnglish
French
Published 31.07.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
AbstractList The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
Author WOLTERING, THOMAS
KUGLSTATTER, ANDREAS
OBST SANDER, ULRIKE
WOSTL, WOLFGANG
HILPERT, HANS
LIMBERG, ANJA
GUBA, WOLFGANG
PINARD, EMMANUEL
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– fullname: KUGLSTATTER, ANDREAS
– fullname: WOSTL, WOLFGANG
– fullname: LIMBERG, ANJA
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DocumentTitleAlternate FLUORO-[1,3]OXAZINES SERVANT D'INHIBITEURS DE LA BACE1
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Snippet The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title FLUORO-[1,3]OXAZINES AS BACE1 INHIBITORS
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