TRIAZOLONE COMPOUNDS AND USES THEREOF
The invention disclosed herein is directed to compounds of Formula I [Formula should be inserted here] and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The inventio...
Saved in:
Main Authors | , , , , , , |
---|---|
Format | Patent |
Language | English French |
Published |
26.06.2014
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The invention disclosed herein is directed to compounds of Formula I [Formula should be inserted here] and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula I, or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a therapeutically effective amount of a selective PPARa antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. |
---|---|
AbstractList | The invention disclosed herein is directed to compounds of Formula I [Formula should be inserted here] and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula I, or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a therapeutically effective amount of a selective PPARa antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. |
Author | CHEN, AUSTIN CHIH-YU BRAVO, YALDA MOSTOFI CLARK, RYAN CHRISTOPHER BACCEI, JILL MELISSA JACINTHO, JASON DUARTE STEARNS, BRIAN ANDREW STOCK, NICHOLAS SIMON |
Author_xml | – fullname: BACCEI, JILL MELISSA – fullname: STOCK, NICHOLAS SIMON – fullname: CHEN, AUSTIN CHIH-YU – fullname: CLARK, RYAN CHRISTOPHER – fullname: STEARNS, BRIAN ANDREW – fullname: JACINTHO, JASON DUARTE – fullname: BRAVO, YALDA MOSTOFI |
BookMark | eNrjYmDJy89L5WRQDQnydIzy9_H3c1Vw9vcN8A_1cwlWcPRzUQgNdg1WCPFwDXL1d-NhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHOjkYWliZGFoaOhsZEKAEATogksw |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | COMPOSES DE TRIAZOLONE ET LEURS UTILISATIONS |
ExternalDocumentID | CA2894281A1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_CA2894281A13 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 13:06:26 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_CA2894281A13 |
Notes | Application Number: CA20132894281 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140626&DB=EPODOC&CC=CA&NR=2894281A1 |
ParticipantIDs | epo_espacenet_CA2894281A1 |
PublicationCentury | 2000 |
PublicationDate | 20140626 |
PublicationDateYYYYMMDD | 2014-06-26 |
PublicationDate_xml | – month: 06 year: 2014 text: 20140626 day: 26 |
PublicationDecade | 2010 |
PublicationYear | 2014 |
RelatedCompanies | INCEPTION 2, INC |
RelatedCompanies_xml | – name: INCEPTION 2, INC |
Score | 2.9319084 |
Snippet | The invention disclosed herein is directed to compounds of Formula I [Formula should be inserted here] and pharmaceutically acceptable salts thereof, which are... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | TRIAZOLONE COMPOUNDS AND USES THEREOF |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140626&DB=EPODOC&locale=&CC=CA&NR=2894281A1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_GFPVNp-L8Ig_at-K6td18KNIlKVVsU2orw5fRjxT2Moer-O97Dd30Rd9CAknu4PK7X3J3AbiZVMZYIk7o9-is6mZhl_pkJDN9UCA4ZJZRmipdLAhtPzWfZtasA4tNLoyqE_qliiOiRRVo77U6r1c_l1hMxVau7_IFdr0_eInDtJYdI1tAB11jU4dHggmqUepQVwtjB3kFOtqGi0Rpp_GimzL7_HXaJKWsfiOKdwi7EU62rI-gI5c92Kebj9d6sBe0793YbE1vfQy3SfzovolnEXJCRRCJNGQvxA0ZSfFIJInPYy68EyAeT6iv43rzrWxz6m53NjqFLlJ-eQakHBuFRHHyoWmZBUKGUVWZhfZXWdIe5Fkf-n9Oc_7P2AUcNEpqQp2G9iV0649PeYWgWufXSh3fvz52oQ |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT4NAEJ401VhvWjW2vjgoN2JpedQDMXSBUAWWIJjGC-GxJL3UxmL8-w4bWr3obbOb7O5MMvvNtzszC3A7rWSdIU5ID-isSkqhldJ0wjJpVCA4ZKpcKjxdzA80N1GeFuqiA8ttLgyvE_rFiyOiRRVo7zU_r9c_l1gWj63c3OdL7Hp_dGLDElt2jGwBHXTRmhl2SC1KREIMYopBZCCvQEdbNpEo7elNcd7Gc3qdNUkp69-I4hzBfoiTrepj6LBVH3pk-_FaHw789r0bm63pbU7gLo7m5hv1aGALhPohTQLrRTADS0jwSBRi145s6pyC4NgxcSVcL93JlhJzt7PJGXSR8rNzEEpdLhiKk48VVSkQMuSqylS0v0pl2ijPBjD4c5rhP2M30HNj30u9efB8AYeNwpqwp7F2Cd3645NdIcDW-TVXzTdzKnmO |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=TRIAZOLONE+COMPOUNDS+AND+USES+THEREOF&rft.inventor=BACCEI%2C+JILL+MELISSA&rft.inventor=STOCK%2C+NICHOLAS+SIMON&rft.inventor=CHEN%2C+AUSTIN+CHIH-YU&rft.inventor=CLARK%2C+RYAN+CHRISTOPHER&rft.inventor=STEARNS%2C+BRIAN+ANDREW&rft.inventor=JACINTHO%2C+JASON+DUARTE&rft.inventor=BRAVO%2C+YALDA+MOSTOFI&rft.date=2014-06-26&rft.externalDBID=A1&rft.externalDocID=CA2894281A1 |