TARGETING AMINOACID LIPIDS
81781396 Abstract The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands (see formula I) and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioa...
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| Main Authors | , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
06.07.2021
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| Subjects | |
| Online Access | Get full text |
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| Abstract | 81781396 Abstract The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands (see formula I) and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. The present invention is further directed to methods of their preparation and their uses in medical applications, such as targeted delivery of bioactive agents to specific tissues or cells and antigen display systems for the study, diagnosis, and treatment of traits, diseases and conditions that respond to said bioactive agents. R3 N --L S2 N (C1126 S3 ): 0 y¨sc¨x1 Date Recue/Date Received 2020-10-09
Cette invention concerne des systèmes porteurs comprenant un complexe éther-lipides conjugué à un ou plusieurs ligands bioactifs et exposé à la surface du système porteur pour être utilisé dans des systèmes d'administration ciblée et/ou de présentation d'antigènes. Eventuellement un ou plusieurs agents bioactifs supplémentaires peuvent être encapsulés ou incorporés dans le système porteur ou attachés ou adsorbés sur sa surface. Cette invention concerne en outre des procédés pour les préparer et leurs utilisations dans des applications médicales, telles que l'administration ciblée d'agents bioactifs à des tissus ou des cellules spécifiques et des systèmes de présentation d'antigènes pour l'étude, le diagnostic, et le traitement de traits, de maladies et d'affections qui réagissent auxdits agents bioactifs. |
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| AbstractList | 81781396 Abstract The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands (see formula I) and exposed on the surface of the carrier system for use in targeted delivery and/or antigen display systems. Optionally one or more further bioactive agents may be encapsulated or embedded within or attached to or adsorbed onto the carrier system. The present invention is further directed to methods of their preparation and their uses in medical applications, such as targeted delivery of bioactive agents to specific tissues or cells and antigen display systems for the study, diagnosis, and treatment of traits, diseases and conditions that respond to said bioactive agents. R3 N --L S2 N (C1126 S3 ): 0 y¨sc¨x1 Date Recue/Date Received 2020-10-09
Cette invention concerne des systèmes porteurs comprenant un complexe éther-lipides conjugué à un ou plusieurs ligands bioactifs et exposé à la surface du système porteur pour être utilisé dans des systèmes d'administration ciblée et/ou de présentation d'antigènes. Eventuellement un ou plusieurs agents bioactifs supplémentaires peuvent être encapsulés ou incorporés dans le système porteur ou attachés ou adsorbés sur sa surface. Cette invention concerne en outre des procédés pour les préparer et leurs utilisations dans des applications médicales, telles que l'administration ciblée d'agents bioactifs à des tissus ou des cellules spécifiques et des systèmes de présentation d'antigènes pour l'étude, le diagnostic, et le traitement de traits, de maladies et d'affections qui réagissent auxdits agents bioactifs. |
| Author | PASSAFARO, MARCO SILVIO HOERTNER, SIMONE RACHEL GROEHN, VIOLA BAUER, FINN BEHRENDT, RAYMOND PLATSCHER, MICHAEL WILHELM |
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| DocumentTitleAlternate | LIPIDES DE CIBLAGE DE TYPE ACIDE AMINE |
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| Snippet | 81781396 Abstract The present invention is directed to carrier systems comprising ether-lipids conjugated to one or more bioactive ligands (see formula I) and... |
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| SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | TARGETING AMINOACID LIPIDS |
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