SPLIT INTEINS AND USES THEREOF

• Main Authors: SCHMIDT, STEFAN ROBERT, CARVAJAL VALLEJOS, PATRICIA KARINA, PALLISSE BERGWERF, ROSER, MARCO FELIU, DIDAC
• Format: Patent
• Language: English; French
• Published: 04.04.2013
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present invention relates generally to robust split inteins. The split inteins described herein are active over a large temperature range, including temperatures as low as 0 ºC, over a wide pH range, and in the presence of chaotropic salts. The split inteins also show high tolerance to sequence...