SUPPRESSION OF CANCER

The present invention relates to polypeptides for use in suppressing cancer and cancer disorders. The treatment employs use of a non-cytotoxic protease, which is targeted to the cancer cell, and, when so delivered, the protease is internalised and inhibits secretion from the cancer cell. L'inve...

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Main Authors MARKS, PHILIP, LECANE, PHILIP, FOSTER, KEITH, MADEC, FREDERIC
Format Patent
LanguageEnglish
French
Published 08.01.2019
Subjects
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Abstract The present invention relates to polypeptides for use in suppressing cancer and cancer disorders. The treatment employs use of a non-cytotoxic protease, which is targeted to the cancer cell, and, when so delivered, the protease is internalised and inhibits secretion from the cancer cell. L'invention porte sur des polypeptides destinés à être utilisés pour supprimer des cancers et des affections cancéreuses. Le traitement utilise une protéase non cytotoxique qui est ciblée sur la cellule cancéreuse et qui, une fois administrée, est internalisée et inhibe la sécrétion par la cellule cancéreuse.
AbstractList The present invention relates to polypeptides for use in suppressing cancer and cancer disorders. The treatment employs use of a non-cytotoxic protease, which is targeted to the cancer cell, and, when so delivered, the protease is internalised and inhibits secretion from the cancer cell. L'invention porte sur des polypeptides destinés à être utilisés pour supprimer des cancers et des affections cancéreuses. Le traitement utilise une protéase non cytotoxique qui est ciblée sur la cellule cancéreuse et qui, une fois administrée, est internalisée et inhibe la sécrétion par la cellule cancéreuse.
Author MADEC, FREDERIC
LECANE, PHILIP
MARKS, PHILIP
FOSTER, KEITH
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Snippet The present invention relates to polypeptides for use in suppressing cancer and cancer disorders. The treatment employs use of a non-cytotoxic protease, which...
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SubjectTerms BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
Title SUPPRESSION OF CANCER
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