NOVEL TYROSINE KINASE INHIBITORS

Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.

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Bibliographic Details
Main Authors MIKEL, CHARLES, YAN, ZHENG, LIU, YAHUA, ZOZULYA, SERGEY, GREGOR, VLAD EDWARD, PICKENS, JASON C, THIRUVAZHI, MOHAN SANTHANAM, ZHU, TONG, KADUSHKIN, ALEXANDER, VAIRAGOUNDAR, RANENDRAN, JIANG, LUYONG, VAVILALA, GOVERDHAN REDDY, ANIKIN, ALEXEY, CHUCHOLOWSKI, ALEXANDER, KHASANOV, ALISHER, MCGRATH, DOUGLAS ERIC
Format Patent
LanguageEnglish
French
Published 13.09.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
Bibliography:Application Number: CA20092718872