(R)-5-METHYL-4,5-DIHYDRO-PYRAZOLE-1,5-DICARBOXYLIC ACID 1-[(4-CHLOROPHENYL)AMIDE 5-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENNYL)AMIDE) AS A FACTOR XA INHIBITOR

(R) -5 -Methyl -4, 5-dihydro-pyrazole-1, 5 -dicarboxylic acid 1 - [ (4-ch loro -phenyl) -amide] 5- {[2-f luoro-4- (2-oxo-2H-pyridin-1 -yl) -phenyl] -a mide) pharmaceutical compositions, methods and methods of using the compound or pharmaceutical compositions thereof to treat diseases characterized b...

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Bibliographic Details
Main Authors EDMUNDS, JEREMY JOHN, SAMAS, BRIAN MATTHEW
Format Patent
LanguageEnglish
French
Published 05.06.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:(R) -5 -Methyl -4, 5-dihydro-pyrazole-1, 5 -dicarboxylic acid 1 - [ (4-ch loro -phenyl) -amide] 5- {[2-f luoro-4- (2-oxo-2H-pyridin-1 -yl) -phenyl] -a mide) pharmaceutical compositions, methods and methods of using the compound or pharmaceutical compositions thereof to treat diseases characterized by a bnormal thrombosis in mammals. A crystalline form of (R) -5-Methyl-4, 5-dihy dro-pyrazole-1, 5 -dicarboxylic acid 1-[(4- chloro- phenyl) -amide] 5- { [2- fluoro-4- (2-oxo-2H-pyridin-1 -yl) -phenyl] -amide} is also described. Formu la (I):
Bibliography:Application Number: CA20072670595