STEREOSELECTIVE HYDROGENATION PROCESS FOR PREPARING CIS-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYL]-2-METHOXY-5,6,7,8-TETRAHYDRONAPHTHALENE HYDROCHLORIDE
This invention provides an improved process for preparing cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-2-methoxy-5,6,7,8-tetrahydronaphthalene hydrochloride which is an intermediate for the preparation of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]- 5,6,7,8-tetrahydronaphthale...
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| Main Authors | , |
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| Format | Patent |
| Language | English French |
| Published |
14.09.2010
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| Subjects | |
| Online Access | Get full text |
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| Abstract | This invention provides an improved process for preparing cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-2-methoxy-5,6,7,8-tetrahydronaphthalene hydrochloride which is an intermediate for the preparation of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]- 5,6,7,8-tetrahydronaphthalene-2-ol which is useful for the treatment of osteoporosis.
L'invention concerne un procédé amélioré de préparation de is-6-phényl-5-[4-(2- pyrrolidin-1 -yl-éthoxy)-phényl]-2-méthoxy-5,6,7,8-tétrahydronaphtalène qui est un intermédiaire pour la préparation de (-)-cis-6-phényl-5-[4-(2-pyrrolidin-1 -yl-éthoxy)-phényl]- 5,6,7,8-tétrahydronaphtalène-2-ol, utilisé pour le traitement de l'ostéoporose. |
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| AbstractList | This invention provides an improved process for preparing cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-2-methoxy-5,6,7,8-tetrahydronaphthalene hydrochloride which is an intermediate for the preparation of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]- 5,6,7,8-tetrahydronaphthalene-2-ol which is useful for the treatment of osteoporosis.
L'invention concerne un procédé amélioré de préparation de is-6-phényl-5-[4-(2- pyrrolidin-1 -yl-éthoxy)-phényl]-2-méthoxy-5,6,7,8-tétrahydronaphtalène qui est un intermédiaire pour la préparation de (-)-cis-6-phényl-5-[4-(2-pyrrolidin-1 -yl-éthoxy)-phényl]- 5,6,7,8-tétrahydronaphtalène-2-ol, utilisé pour le traitement de l'ostéoporose. |
| Author | LEHNER, RICHARD SHELTON TABER, GERALDINE PATRICIA |
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| DocumentTitleAlternate | PROCEDE D'HYDROGENATION STEREOSELECTIVE LA PREPARATION DE CHLORHYDRATE DE CIS-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYL]-2-METHOXY-5,6,7,8-TETRAHYDRONAPHTALENE |
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| Snippet | This invention provides an improved process for preparing cis-6-phenyl-5-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-2-methoxy-5,6,7,8-tetrahydronaphthalene... |
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| Title | STEREOSELECTIVE HYDROGENATION PROCESS FOR PREPARING CIS-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYL]-2-METHOXY-5,6,7,8-TETRAHYDRONAPHTHALENE HYDROCHLORIDE |
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