HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES

The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods and intermediates for preparing such compounds. In another embodiment, the invention discloses pharm...

Full description

Saved in:
Bibliographic Details
Main Authors HIPSKIND, PHILIP ARTHUR, JESUDASON, CYNTHIA DARSHINI, PICKARD, RICHARD TODD, BEAVERS, LISA SELSAM, TAKAKUWA, TAKAKO, GADSKI, ROBERT ALAN, HORNBACK, WILLIAM JOSEPH
Format Patent
LanguageEnglish
French
Published 14.01.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

Abstract The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods and intermediates for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
AbstractList The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or inverse agonist activity, as well as methods and intermediates for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
Author BEAVERS, LISA SELSAM
PICKARD, RICHARD TODD
GADSKI, ROBERT ALAN
TAKAKUWA, TAKAKO
JESUDASON, CYNTHIA DARSHINI
HIPSKIND, PHILIP ARTHUR
HORNBACK, WILLIAM JOSEPH
Author_xml – fullname: HIPSKIND, PHILIP ARTHUR
– fullname: JESUDASON, CYNTHIA DARSHINI
– fullname: PICKARD, RICHARD TODD
– fullname: BEAVERS, LISA SELSAM
– fullname: TAKAKUWA, TAKAKO
– fullname: GADSKI, ROBERT ALAN
– fullname: HORNBACK, WILLIAM JOSEPH
BookMark eNqFyr0KwjAQAOAMOvj3DN4DKEhSHIXjPE0G05Bc51LknCQt1PfHxd3pW761WdSx6spcfCiCjxAZvIPMxEnaDHjnKOUAKXPCjBLaCBivIJ4zJu4kEHSFy9YsX8N71t3PjdnfWMgfdRp7nafhqVU_PaE9n6x1Dbn_4wuwRSrU
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate AGENTS AGISSANT SUR LE RECEPTEUR H3 DE L'HISTAMINE, LEUR PREPARATION ET LEURS UTILISATIONS THERAPEUTIQUES
ExternalDocumentID CA2602234C
GroupedDBID EVB
ID FETCH-epo_espacenet_CA2602234C3
IEDL.DBID EVB
IngestDate Fri Jul 19 15:57:22 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
French
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_CA2602234C3
Notes Application Number: CA20062602234
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140114&DB=EPODOC&CC=CA&NR=2602234C
ParticipantIDs epo_espacenet_CA2602234C
PublicationCentury 2000
PublicationDate 20140114
PublicationDateYYYYMMDD 2014-01-14
PublicationDate_xml – month: 01
  year: 2014
  text: 20140114
  day: 14
PublicationDecade 2010
PublicationYear 2014
RelatedCompanies ELI LILLY AND COMPANY
RelatedCompanies_xml – name: ELI LILLY AND COMPANY
Score 2.919679
Snippet The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine-H3 receptor antagonist or...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20140114&DB=EPODOC&locale=&CC=CA&NR=2602234C
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3NT8IwFH9BNOpNUYPfPZidJDLoRjlMU7riMGEsoxhuZsMuehlEZvz3fZ2gXji0adrkpX3J73217xXgJmm1OplLdQObKaqt7UYya3awcxJNM-Y0bZPvPAzdYEKfps60Am_rXJiyTuhXWRwRETVDvBelvF78BbH88m3l8i59x6n5Q195vrXyjo23YFPL73kyGvkjYQnhCW6FsYdmOypCKrZgG43ojsGCfO6ZnJTFf4XSP4CdCGnlxSFUdF6DPbH-d60Gu8PVdTcOV8hbHsF9MBgrPhyEkgRtEkshIzWKCX-UoRrfEmRkxH_iTYSHPlGBjHkkJ2ogyARF5jFc96USQQM38vJ75hfB1ztun0A1n-e6DiRD78ZpZylNXU1fZylLEEDMTVm3xVjXZadQ30TlbPPSOewbzpm4gk0voFp8fOpL1LRFelUy6RvPQXzC
link.rule.ids 230,309,783,888,25576,76876
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3NT8IwFH9BNOJNUYOf9GB2ksigG-MwTemKm7KxjGK4LRtu0csgMuO_79sE9cKhTdMmL-1Lfu-rfa8AN1Gn00t1mrSwFUW1E7UVzds97LQooamhtdUi39n1dHtKn2barAJvm1yYsk7oV1kcERE1R7znpbxe_gWxrPJt5eoufsepxcNQmpay9o4Lb0GlijUwhT-2xlzh3ORM8QITzXZUhJTvwC4a2L0CC-JlUOSkLP8rlOEh7PlIK8uPoJJkdajxzb9rddh319fdOFwjb3UM97Yzkcx1PEHsLgkEF74cB4Q9Ck9Obgky0mc_8SbCPItIWwTMF1PpcDJFkXkCzaGQ3G7hRsLfM4ecbXbcPYVqtsiSBpAUvRutm8Y01hP6Oo-NCAFk6LHR7xhGXzfOoLGNyvn2pSbUbOmOwpHjPV_AQcHFIsag0kuo5h-fyRVq3Ty-Lhn2DdSyf7U
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=HISTAMINE+H3+RECEPTOR+AGENTS%2C+PREPARATION+AND+THERAPEUTIC+USES&rft.inventor=HIPSKIND%2C+PHILIP+ARTHUR&rft.inventor=JESUDASON%2C+CYNTHIA+DARSHINI&rft.inventor=PICKARD%2C+RICHARD+TODD&rft.inventor=BEAVERS%2C+LISA+SELSAM&rft.inventor=TAKAKUWA%2C+TAKAKO&rft.inventor=GADSKI%2C+ROBERT+ALAN&rft.inventor=HORNBACK%2C+WILLIAM+JOSEPH&rft.date=2014-01-14&rft.externalDBID=C&rft.externalDocID=CA2602234C