DEPOT FORMULATION COMPRISING CEFTIOFUR AND PEROXIDIZED NATURAL OIL

A composition comprising crystalline ceftiofur free acid and a liquid carrier, wherein said liquid carrier comprises an unsaturated oil having a peroxide value of between 0.1 and 600 milliequivalents (mEq) of peroxide per 1000 grams of oil. The composition is useful for the sustained release of crys...

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Main Authors SU, CHINGIANG, KING, HARRY M, HUDA, SYED F, WALDRON, NIKI A, TEAGARDEN, DIRK L, WHITMIRE, MONICA L, SCHAPAUGH, RANDAL LEE, EATON, LESLIE C, BRITTEN, NANCY J, BROWN, SCOTT A, MACHKOVECH, SUSAN M, URBAN, TERRY R, STEELE, JEAN M, SPEAKER, STANLEY M, CAPUTO, JAMES F, HENDL, ONDREJ
Format Patent
LanguageEnglish
French
Published 31.05.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A composition comprising crystalline ceftiofur free acid and a liquid carrier, wherein said liquid carrier comprises an unsaturated oil having a peroxide value of between 0.1 and 600 milliequivalents (mEq) of peroxide per 1000 grams of oil. The composition is useful for the sustained release of crystalline ceftiofur free is the treatment of bacterial infections in mammalian animals. Compositions according to the invention have an improved shelf-life and retain the original sustained release properties and performance for extended periods of time.
Bibliography:Application Number: CA20012416566