CONJUGATED FATTY ACIDS AND RELATED COMPOUNDS, AND METHOD FORTHEIR ENZYMATIC PREPARATION

• Main Authors: CHRISTIE, WILLIAM WALKER, SLABAS, ANTONI RYSZARD, SAEBO, ASGEIR, SIMON, JOSIAH WILLIAM
• Format: Patent
• Language: English; French
• Published: 21.06.2001
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; BEER; BIOCHEMISTRY; CHEMISTRY; EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKINGOILS; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; FOODS OR FOODSTUFFS; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES USING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

It has been demonstrated that conjugated linoleic acid isomers with the firs t double bond in position 9 (cis) or 10 (trans), added exogenously, can be desaturated in position 6 by the cyanobacterium Spirulina platensis. The metabolites, 6-cis, 9-cis, 11-trans-octadecatrienoic and 6-cis, 10-trans, 12 - cis-octadecatrienoic acids, which have not previously been characterized, we re isolated by a combination of chromatographic techniques and the structures were confirmed by gas chromatography-mass spectrometry in the form of picolinyl ester and dimethyloxazoline derivatives.