SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR XA INHIBITORS

• Main Authors: MYERS, MICHAEL R, EWING, WILLIAM R, LI, AIWEN, POLI, GREGORY B, LAU, WAN F, BECKER, MICHAEL R, CONDON, STEPHEN M, PAULS, HEINZ W, BURNS, CHRISTOPHER J, HANNEY, BARBARA A, SPADA, ALFRED P, HE, WEI, JIANG, JOHN Z, CHOI-SLEDESKI, YONG MI, DAVIS, RODERICK S
• Format: Patent
• Language: English; French
• Published: 22.02.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

This invention is directed to oxoazaheterocyclyl compounds which inhibit factor Xa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds and to a method of inhibiting factor Xa.