AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS
The present invention discloses peptide aldehydes of formula (I) which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterize...
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| Main Authors | , , , , , , , , , |
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| Format | Patent |
| Language | English French |
| Published |
20.06.1996
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| Edition | 6 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention discloses peptide aldehydes of formula (I) which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis. |
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| AbstractList | The present invention discloses peptide aldehydes of formula (I) which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis. |
| Author | TAMURA, SUSAN YOSHIKO NUTT, RUTH F CARPENTER, STEPHEN H BRUNCK, TERENCE KEVIN LIM-WILBY, MARGUERITA S GE, YU RIPKA, WILLIAM CHARLES SEMPLE, JOSEPH EDWARD ARDECKY, ROBERT JOHN ABELMAN, MATTHEW MARK |
| Author_xml | – fullname: SEMPLE, JOSEPH EDWARD – fullname: ARDECKY, ROBERT JOHN – fullname: NUTT, RUTH F – fullname: GE, YU – fullname: RIPKA, WILLIAM CHARLES – fullname: ABELMAN, MATTHEW MARK – fullname: CARPENTER, STEPHEN H – fullname: TAMURA, SUSAN YOSHIKO – fullname: BRUNCK, TERENCE KEVIN – fullname: LIM-WILBY, MARGUERITA S |
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| DocumentTitleAlternate | DERIVES AROMATIQUES HETEROCYCLIQUES UTILISABLES COMME INHIBITEURS D'ENZYMES |
| Edition | 6 |
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| PublicationDateYYYYMMDD | 1996-06-20 |
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| PublicationDecade | 1990 |
| PublicationYear | 1996 |
| RelatedCompanies | CORVAS INTERNATIONAL, INC |
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| Snippet | The present invention discloses peptide aldehydes of formula (I) which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts,... |
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| SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | AROMATIC HETEROCYCLIC DERIVATIVES AS ENZYME INHIBITORS |
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