SUBSTITUTED ARYL UREAS AS HIGH POTENCY SWEETENERS

• Main Authors: CULBERSON, JOHN C, DUBOIS, GRANT E, CARTER, JEFFERY S, KLADE, CARRIE A, NAGARAJAN, SRIVIVASAN, KLIX, RUSSELL C, MULLER, GEORGE W, MADIGAN, DAROLD L, WALTERS, D. ERIC, AGER, DAVID J
• Format: Patent
• Language: English; French
• Published: 22.10.1996
• Edition: 6
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; METALLURGY; ORGANIC CHEMISTRY; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

Substituted ureas and thioureas of the formula wherein X1 is O or S and R2, R3, R4 and R5 are variously defined, are disclosed for use as high potency sweeteners. The substituted ureas and thioureas are prepared, in a preferred method, by reacting an isocyanate or isothiocyanate with an amine or ani...