PROCESS FOR THE PREPARATION OF HYDROCHLORIDES

PROCESS FOR THE PREPARATION OF HYDROCHLIRIDES A b s t r a c t The invention relates to a process for the preparation of hydrochlorides, i.e. of acid addition salts formed with hydrochloric acid, particularly of compounds containing a protonatable nitrogen atom According to the process of the inventi...

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Bibliographic Details
Main Authors KUN, LAJOS, CSEKE, LASZLO, BALINT, JANOS, SZARVAS, MIKLOS, HORVATH, EVA (NEE FEHER), FABIAN, FERENC
Format Patent
LanguageEnglish
French
Published 29.07.1986
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMISTRY
DERIVATIVES THEREOF
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
STEROIDS
SUGARS
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Summary:PROCESS FOR THE PREPARATION OF HYDROCHLIRIDES A b s t r a c t The invention relates to a process for the preparation of hydrochlorides, i.e. of acid addition salts formed with hydrochloric acid, particularly of compounds containing a protonatable nitrogen atom According to the process of the invention a compound useful to form a hydrochloride and being suitably in the form of a derivative containing protonatable nitrogen atom or in the form of a salt is reacted with a sulphonyl compound of the formula Q - SO2 - Cl, wherein Q stands for a hydroxyl, C1-4 alkyl or an aryl group, the latter being optionally substituted by a C1-4 alkyl group, in a solvent, in the presence of an alcohol, whereupon the hydrochloride obtained is recovered in a known manner.
Bibliography:Application Number: CA19840452850