COMPOSTOS HETEROARILA, COMPOSIÇÃO FARMACÊUTICA E SEUS USOS COMO INIBIDORES DA ALDOSTERONA SINTASE

A presente invenção refere-se a compostos da Fórmula I: (I) e sais farmaceuticamente aceitáveis dos mesmos, em que Cy, R1 e R2 são como aqui definidos. A invenção também se refere a composições farmacêuticas compreendendo esses compostos, a métodos para utilizar esses compostos no tratamento de vári...

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Main Authors LEE FADER, BRYAN P. MCKIBBEN, JOHN LORD, SIMON SURPRENANT, DANIEL RICHARD MARSHALL, MATTHEW A. CERNY, YUNLONG ZHANG, MAOLIN YU, KOSEA S. FREDERICK, DEREK COGAN, JENNIFER BURKE
Format Patent
LanguagePortuguese
Published 26.07.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract A presente invenção refere-se a compostos da Fórmula I: (I) e sais farmaceuticamente aceitáveis dos mesmos, em que Cy, R1 e R2 são como aqui definidos. A invenção também se refere a composições farmacêuticas compreendendo esses compostos, a métodos para utilizar esses compostos no tratamento de várias doenças e transtornos e a processos para preparar esses compostos e intermediários úteis nesses processos. The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein Cy, R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
AbstractList A presente invenção refere-se a compostos da Fórmula I: (I) e sais farmaceuticamente aceitáveis dos mesmos, em que Cy, R1 e R2 são como aqui definidos. A invenção também se refere a composições farmacêuticas compreendendo esses compostos, a métodos para utilizar esses compostos no tratamento de várias doenças e transtornos e a processos para preparar esses compostos e intermediários úteis nesses processos. The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein Cy, R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
Author YUNLONG ZHANG
MAOLIN YU
KOSEA S. FREDERICK
DEREK COGAN
BRYAN P. MCKIBBEN
JENNIFER BURKE
LEE FADER
SIMON SURPRENANT
JOHN LORD
MATTHEW A. CERNY
DANIEL RICHARD MARSHALL
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– fullname: MATTHEW A. CERNY
– fullname: YUNLONG ZHANG
– fullname: MAOLIN YU
– fullname: KOSEA S. FREDERICK
– fullname: DEREK COGAN
– fullname: JENNIFER BURKE
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Snippet A presente invenção refere-se a compostos da Fórmula I: (I) e sais farmaceuticamente aceitáveis dos mesmos, em que Cy, R1 e R2 são como aqui definidos. A...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title COMPOSTOS HETEROARILA, COMPOSIÇÃO FARMACÊUTICA E SEUS USOS COMO INIBIDORES DA ALDOSTERONA SINTASE
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