BIOSSENSOR E MÉTODO PARA PRODUZIR UM BIOSSENSOR

BIOSSENSOR E MÉTODO PARA PRODUZIR UM BIOSSENSOR. Um biossensor, que inclui uma base de dispositivo tendo um conjunto de sensores e uma disposição de guias de guias de luz. Os guias de luz têm regiões de entrada, que são configuradas para receber luz de excitação e emissões de luz geradas por substân...

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Main Authors DARREN SEGALE, CHENG FRANK ZHONG, HOD FINKELSTEIN, BOYAN BOYANOV, DIETRICH DEHLINGER
Format Patent
LanguagePortuguese
Published 08.08.2017
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Abstract BIOSSENSOR E MÉTODO PARA PRODUZIR UM BIOSSENSOR. Um biossensor, que inclui uma base de dispositivo tendo um conjunto de sensores e uma disposição de guias de guias de luz. Os guias de luz têm regiões de entrada, que são configuradas para receber luz de excitação e emissões de luz geradas por substâncias biológicas ou químicas. Os guias de luz se estendem para a base do dispositivo no sentido de sensores de luz correspondentes e têm um material filtrante. A base do dispositivo inclui um conjunto de circuitos, acoplado eletricamente aos sensores de luz e configurado para transmitir sinais de dados. O biossensor também inclui uma camada de blindagem tendo aberturas, que são posicionadas relativas às regiões de entrada dos guias de luz correspondentes, de modo que as emissões de luz se propaguem pelas aberturas para as regiões de entrada correspondentes. A camada de blindagem se estende entre as aberturas adjacentes e é configurada para bloquear a luz de excitação e as emissões de luz incidentes na camada de blindagem entre as aberturas adjacentes. Biosensor comprising a flow cell and a detection device having the flow cell coupled thereto, the flow cell and the detection device forming a flow channel that is configured to have biological or chemical substances therein that generate light emissions in response to an excitation light, the detection device including a device base having a sensor array of light sensors and a guide array of light guides, the light guides configured to receive the excitation light and the light emissions from the flow channel, each of the light guides extending into the device base along a central longitudinal axis from an input region of the light guide toward a corresponding light sensor of the sensor array, the light guides including a filter material that is configured to filter the excitation light and permit the light emissions to propagate therethrough toward the corresponding light sensors, the device base including device circuitry that is electrically coupled to the light sensors and configured to transmit data signals based on photons detected by the light sensors; wherein the device base includes peripheral crosstalk shields located therein that at least partially surround corresponding light guides of the guide array, the crosstalk shields at least partially surrounding the corresponding light guides about the respective longitudinal axis to reduce optical crosstalk between adjacent light sensors.
AbstractList BIOSSENSOR E MÉTODO PARA PRODUZIR UM BIOSSENSOR. Um biossensor, que inclui uma base de dispositivo tendo um conjunto de sensores e uma disposição de guias de guias de luz. Os guias de luz têm regiões de entrada, que são configuradas para receber luz de excitação e emissões de luz geradas por substâncias biológicas ou químicas. Os guias de luz se estendem para a base do dispositivo no sentido de sensores de luz correspondentes e têm um material filtrante. A base do dispositivo inclui um conjunto de circuitos, acoplado eletricamente aos sensores de luz e configurado para transmitir sinais de dados. O biossensor também inclui uma camada de blindagem tendo aberturas, que são posicionadas relativas às regiões de entrada dos guias de luz correspondentes, de modo que as emissões de luz se propaguem pelas aberturas para as regiões de entrada correspondentes. A camada de blindagem se estende entre as aberturas adjacentes e é configurada para bloquear a luz de excitação e as emissões de luz incidentes na camada de blindagem entre as aberturas adjacentes. Biosensor comprising a flow cell and a detection device having the flow cell coupled thereto, the flow cell and the detection device forming a flow channel that is configured to have biological or chemical substances therein that generate light emissions in response to an excitation light, the detection device including a device base having a sensor array of light sensors and a guide array of light guides, the light guides configured to receive the excitation light and the light emissions from the flow channel, each of the light guides extending into the device base along a central longitudinal axis from an input region of the light guide toward a corresponding light sensor of the sensor array, the light guides including a filter material that is configured to filter the excitation light and permit the light emissions to propagate therethrough toward the corresponding light sensors, the device base including device circuitry that is electrically coupled to the light sensors and configured to transmit data signals based on photons detected by the light sensors; wherein the device base includes peripheral crosstalk shields located therein that at least partially surround corresponding light guides of the guide array, the crosstalk shields at least partially surrounding the corresponding light guides about the respective longitudinal axis to reduce optical crosstalk between adjacent light sensors.
Author HOD FINKELSTEIN
DIETRICH DEHLINGER
CHENG FRANK ZHONG
BOYAN BOYANOV
DARREN SEGALE
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Snippet BIOSSENSOR E MÉTODO PARA PRODUZIR UM BIOSSENSOR. Um biossensor, que inclui uma base de dispositivo tendo um conjunto de sensores e uma disposição de guias de...
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Title BIOSSENSOR E MÉTODO PARA PRODUZIR UM BIOSSENSOR
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