carboditioato e o processo de preparação do mesmo

• Main Authors: TARA RAWAT, LALIT KUMAR, VISHANU LAL SHARMA, LOKESH KUMAR, AMIT SARSWAT, ASHISH JAIN, SANTOSH JANGIR, NAND LAL, VEENU BALA, JAGDAMBA PRASAD MAIKHURI, GOPAL GUPTA
• Format: Patent
• Language: Portuguese
• Published: 18.07.2017
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

resumo carboditioato e o processo de preparação do mesmo a presente invenção refere-se à síntese e avaliação biológica de compostos de fórmula i como agentes espermicidas, e o seu sal de ácido farmaceuticamente aceitável. a invenção proporciona bis (4- substituído-1-piperazinilthiocarbonil) dissulfureto (quando n = 0) e alcano-1, n-di-ilbis (4-substituído piperazina-1-carboditioato) (quando n = 0, 1, 2 ou 3) como mostrado na figura 1 do desenho anexo. estes compostos são considerados úteis para a actividade espermicida. fórmula i The present invention relates to the synthesis and biological evaluation of compound of formula I as spermicidal agents, and its pharmaceutically acceptable acid salt thereof. The invention provides bis(4- substituted-1-piperazinylthiocarbonyl) disulfide (when n = 0) and alkane-1,n-diylbis(4-substituted piperazine-1-carbodithioate) (when n = 0, 1, 2 or 3) as shown in figure 1 of the accompanying drawing. These compounds are found to be useful for spermicidal activity.