TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES
Съединенията с формула@@в която значенията на заместителите са посочени в описанието, са поли(ADP-рибозол)трансферазни (PARP) инхибитори и са полезникато терапевтични средства при лечението на ракови заболявания и за подобряване ефектите при удари, травми и невродегенеративни заболявания. Те могат д...
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| Main Authors | , , , |
|---|---|
| Format | Patent |
| Language | Bulgarian English |
| Published |
31.07.2007
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Съединенията с формула@@в която значенията на заместителите са посочени в описанието, са поли(ADP-рибозол)трансферазни (PARP) инхибитори и са полезникато терапевтични средства при лечението на ракови заболявания и за подобряване ефектите при удари, травми и невродегенеративни заболявания. Те могат да бъдат използвани като ракови терапевтични средства, например в комбинация с цитотоксични средства и/или облъчване.
Compounds of formula are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapeutics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and neurodegenerative disease. As cancer therapeutics, the compounds of the invention may be used, e. g. in combination with cytotoxic agents and/or radiation. |
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| AbstractList | Съединенията с формула@@в която значенията на заместителите са посочени в описанието, са поли(ADP-рибозол)трансферазни (PARP) инхибитори и са полезникато терапевтични средства при лечението на ракови заболявания и за подобряване ефектите при удари, травми и невродегенеративни заболявания. Те могат да бъдат използвани като ракови терапевтични средства, например в комбинация с цитотоксични средства и/или облъчване.
Compounds of formula are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapeutics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and neurodegenerative disease. As cancer therapeutics, the compounds of the invention may be used, e. g. in combination with cytotoxic agents and/or radiation. |
| Author | TIKHE JAYASHREE THORESEN LARS CANAN-KOCH STACIE WEBBER STEPHEN |
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| DocumentTitleAlternate | ТРИЦИКЛИЧНИ ИНХИБИТОРИ НА ПОЛИ (ADP-РИБОЗА) ПОЛИМЕРАЗИ |
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| Notes | Application Number: BG20010105811 |
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| RelatedCompanies | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED AGOURON PHARMACEUTICALS, INC |
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| Snippet | Съединенията с формула@@в която значенията на заместителите са посочени в описанието, са поли(ADP-рибозол)трансферазни (PARP) инхибитори и са полезникато... |
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| Title | TRICYCLIC INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASES |
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