XANTHINE DERIVATIVES

3-Alkyl-7-oxoalkylxanthines of the formula in which Alk is C1-C12 alkyl, and A is a C2-C6-alkylene radical, are prepared. These compounds are obtained by reacting a 3-monoalkylxanthine alkali metal salt at elevated temperature with an appropriate halo ketone to introduce the group -ACOCH3 in positio...

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Bibliographic Details
Main Authors MANFRED JAYME, WERNER MOHLER, JAROMIR KOMAREK
Format Patent
LanguageEnglish
Published 02.06.1977
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:3-Alkyl-7-oxoalkylxanthines of the formula in which Alk is C1-C12 alkyl, and A is a C2-C6-alkylene radical, are prepared. These compounds are obtained by reacting a 3-monoalkylxanthine alkali metal salt at elevated temperature with an appropriate halo ketone to introduce the group -ACOCH3 in position 7. The compounds can be used as vasodilators.
Bibliography:Application Number: AU19750087115