Use of tricyclic 1,4-dihydro-1,4-dioxo-1h-naphthalene derivatives, resulting novel compounds and therapeutical use thereof

• Main Authors: OLIVIER TEMBO, YANNIC-ARNOULT SYLVIE, STEPHANIE DESQUAND-BILLIALD, JEAN-LUC TORREGROSA, ANITA FAVROU, FLORENCE DOMAGALA-LE MARQUER, ODILE BOUTHERIN-FALSON, MICHEL FINET
• Format: Patent
• Language: English
• Published: 24.02.2000
• Edition: 7
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention concerns the therapeutic use of tricyclic salts and their pharmaceutically acceptable salts having the general formula:in which:A is either a sulfur atom, an oxygen atom, or an R3N radical where R3 is a hydrogen atom, a C1-C5 alkyl radical, or a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring.R1 is either a C1-C5 alkyl radical,or an R4NH radical where R4 is a hydrogen atom, a C1-C5 alkyl radical, or a substituted or unsubstituted aromatic ring, or a substituted or unsubstituted heteroaromatic ring,or an aromatic ring that may or may not be substituted by one or more acceptor or donor groups, or a heteroaromatic ring having one or more heteroatoms, which may or may not be substituted by acceptor or donor groups.R2 is a hydrogen atom, halogen atom, a C1-C5 alkyl radical, an oxygen atom that may or may not be substituted by a C1-C5 alkyl radical, or an NR5R5, radical where R5 and R5, are, independently of each other, a hydrogen atom, an oxygen atom or monovalent C1-C5 organic radicals.