CRYSTALLINE (5R,6S)-2-CARBAMOYLOXYMETHYL-6-{(1R)- HYDROXYETHYL}-2-PENEM-CARBOXYLIC ACID AND ITS PHARMACEUTICAL FORMULATION

• Main Authors: STEFANO DEL NERO, PIERLUIGI GRIGGI, CARLO BATTISTINI, SERGIO VIOGLIO, ROBERTO BIANCHINI
• Format: Patent
• Language: English
• Published: 06.08.1992
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A crystalline form of (5R,6S)-2-carbamoyloxymethyl-6-((1R)-hydroxyethyl)-2-penem-3-carboxylic acid incorporates two molecules of water per molecule of the acid and is useful as an antibacterial agent.