BENZODIAZEPINES, PROCESS AND INTERMEDIATES FOR THE PREPARATION THEREOF AND THEIR APPLICATIONS IN THERAPY

• Main Authors: ALAIN PIERRE CALVET, YVES ROBERT PASCAL, FRANCOIS JOSEPH ROMAN, JEAN-LOUIS JUNIEN, XAVIER BERNARD PASCAUD
• Format: Patent
• Language: English
• Published: 12.12.1991
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Benzodiazepines of formula (I) in which R1 is H of halogen, R2 is H or halogen, Ar is indolyl, phenyl, naphthyl, indolyl monosubstituted with a halogen or with a methoxy or phenyl mono-, di- or trisubstituted with a halogen or with a methoxy or with a trifluoromethyl group, and n is 2 or 3; and thei...