Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
Compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents, can be terminally steam sterilized without any significant increase of mean particle size. These compositions display markedly reduced heat-induced c...
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| Main Author | |
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| Format | Patent |
| Language | English |
| Published |
13.12.1999
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| Edition | 6 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents, can be terminally steam sterilized without any significant increase of mean particle size. These compositions display markedly reduced heat-induced coagulation, flocculation, or particle size growth during the terminal steam sterilization process. |
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| AbstractList | Compositions of submicron- to micron-sized particles of water-insoluble biologically active substances that are stabilized by thermoprotecting agents, can be terminally steam sterilized without any significant increase of mean particle size. These compositions display markedly reduced heat-induced coagulation, flocculation, or particle size growth during the terminal steam sterilization process. |
| Author | AWADHESH K. MISHRA |
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| RelatedCompanies | SKYEPHARMA CANADA INC |
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| Title | Thermoprotected microparticle compositions and process for terminal steam sterilization thereof |
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