New process for preparing (-)-trans-n-p-fluorobenzoylmethyl-4-(p-fluorophenyl)-3-{{3,4-(methylenedioxy)phenoxy}methyl}-piperidine

PCT No. PCT/EP97/01007 Sec. 371 Date Oct. 27, 1997 Sec. 102(e) Date Oct. 27, 1997 PCT Filed Feb. 28, 1997 PCT Pub. No. WO97/31915 PCT Pub. Date Sep. 4, 1997The process consists of reacting (-)trans-N-p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo...

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Main Authors SANTIAGO GUBERT, JOSE A ORTIZ, RAFAEL FOGUET, AURELIO SACRISTAN
Format Patent
LanguageEnglish
Published 16.09.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract PCT No. PCT/EP97/01007 Sec. 371 Date Oct. 27, 1997 Sec. 102(e) Date Oct. 27, 1997 PCT Filed Feb. 28, 1997 PCT Pub. No. WO97/31915 PCT Pub. Date Sep. 4, 1997The process consists of reacting (-)trans-N-p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo-4'-fluoroacetophenone. The resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding acid.
AbstractList PCT No. PCT/EP97/01007 Sec. 371 Date Oct. 27, 1997 Sec. 102(e) Date Oct. 27, 1997 PCT Filed Feb. 28, 1997 PCT Pub. No. WO97/31915 PCT Pub. Date Sep. 4, 1997The process consists of reacting (-)trans-N-p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine acetate with 2-chloro- or 2-bromo-4'-fluoroacetophenone. The resulting compound can be isolated as a pharmaceutically acceptable addition salt by reaction with the corresponding acid.
Author AURELIO SACRISTAN
SANTIAGO GUBERT
RAFAEL FOGUET
JOSE A ORTIZ
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Snippet PCT No. PCT/EP97/01007 Sec. 371 Date Oct. 27, 1997 Sec. 102(e) Date Oct. 27, 1997 PCT Filed Feb. 28, 1997 PCT Pub. No. WO97/31915 PCT Pub. Date Sep. 4, 1997The...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title New process for preparing (-)-trans-n-p-fluorobenzoylmethyl-4-(p-fluorophenyl)-3-{{3,4-(methylenedioxy)phenoxy}methyl}-piperidine
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