PTH prodrugs

• Main Authors: Sprogøe, Kennett, Zettler, Joachim, Krusch, Mathias, Maitro, Guillaume, Wegge, Thomas, Cleemann, Felix
• Format: Patent
• Language: English
• Published: 18.01.2024
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Abstract The present invention relates to a PTH prodrug or a pharmaceutically acceptable salt thereof comprising a conjugate D-L, wherein D is a PTH moiety; -L comprises a reversible prodrug linker moiety -L-, which moiety -L 1- is connected to the PTH moiety -D through a functional group of PTH; wh...