3H,4H,5H,6H,7H-PYRIMIDO[4,5-B][1,4]OXAZINE-4,6-DIONE DERIVATIVES AS TRPA1 INHIBITORS
The present disclosure provides certain 3H,4H,5H,6H,7H-pyrimido[4,5- b][1,4]oxazine-4,6-dione derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPAl. Also provided are pharmaceutical c...
Saved in:
| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English |
| Published |
19.09.2024
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present disclosure provides certain 3H,4H,5H,6H,7H-pyrimido[4,5- b][1,4]oxazine-4,6-dione derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPAl. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds. |
|---|---|
| AbstractList | The present disclosure provides certain 3H,4H,5H,6H,7H-pyrimido[4,5- b][1,4]oxazine-4,6-dione derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPAl. Also provided are pharmaceutical compositions containing the same, and processes for preparing said compounds. |
| Author | FLECK, Martin Thomas BINDER, Florian Paul Christian |
| Author_xml | – fullname: BINDER, Florian Paul Christian – fullname: FLECK, Martin Thomas |
| BookMark | eNqNyrsOgjAUANAOOvj6hyaubSKlRR2L1Nw7SEmpRCWEEFMnAyT4_3HxA5zOcpZk1g99WBAfA5PAFLAE2B54cXd4wczWkimeNnXEZGNv-oG54ZIlPEObG5oZh5X2WJmS6pJ6V-iIYg6YoreuXJP5q3tPYfNzRbZn40_Awzi0YRq7Z-jDp9VXsRNCqEOiYn2M_1tflMIx2Q |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | AU2022258653A9 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_AU2022258653A93 |
| IEDL.DBID | EVB |
| IngestDate | Fri Sep 27 05:22:47 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_AU2022258653A93 |
| Notes | Application Number: AU20220258653 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240919&DB=EPODOC&CC=AU&NR=2022258653A9 |
| ParticipantIDs | epo_espacenet_AU2022258653A9 |
| PublicationCentury | 2000 |
| PublicationDate | 20240919 |
| PublicationDateYYYYMMDD | 2024-09-19 |
| PublicationDate_xml | – month: 09 year: 2024 text: 20240919 day: 19 |
| PublicationDecade | 2020 |
| PublicationYear | 2024 |
| RelatedCompanies | BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
| RelatedCompanies_xml | – name: BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
| Score | 3.570265 |
| Snippet | The present disclosure provides certain 3H,4H,5H,6H,7H-pyrimido[4,5- b][1,4]oxazine-4,6-dione derivatives that are inhibitors of transient receptor potential... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | 3H,4H,5H,6H,7H-PYRIMIDO[4,5-B][1,4]OXAZINE-4,6-DIONE DERIVATIVES AS TRPA1 INHIBITORS |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240919&DB=EPODOC&locale=&CC=AU&NR=2022258653A9 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_mFPVNp-LHlIKypwbbNU3XhyH9GqlgW7puTMcYbVdBkG24iv--l7LpnvYWEjiSI3eXu_zuDuBBY7SjvlfoKdMk6G-oRIQaSJq3s0JJqShhJdAWAeMD-jzSRzX43OTCVHVCf6riiChROcp7Wenr5X8Qy62wlavH7AOnFk-9pOu21t4xmicTJdC1u14UuqHTchz0JFtBLNbw5naYrlnmHuzjQ9oQADBvaIu8lOW2UemdwEGE9OblKdSKeQOOnE3vtQYcvqy_vHG4lr7VGSQalymXdS4zLhucRK8xqh43HFNZJ_ZkrMp0Eo6sNz_wCJUZcVFPepKLrtrQSvyh15esvpTEkaVKfsB920_CuH8O9z0vcTjB7U3_uDG1Bttn0S6gPl_Mi0uQstRQqMGUGdMMmmmZaRoKa-dK3hZ9OGfpFTR3UbrevXwDx4K_Aiqhmk2ol1_fxS3a4zK7q9j4CxFOhEM |
| link.rule.ids | 230,309,783,888,25578,76884 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_mFOebTsWPqQVlTw22a5quD0P6NVLd2tJ1YzrGaLsKgnTDVfz3Tcqme9pbSOBIjtxd7vK7O4AHheC2_F6ip3QdMX9DRjzUgOK0lWRSjHkJK4628Agd4uexOq7A5yYXpqwT-lMWR2QSlTJ5L0p9vfwPYtkltnL1mHywqcVTN-rYzbV3zMyTziTQNjtO4Nu-1bQs5kk2vZCvsZvbJqpi6Huwzx7ZbV5p3xmZPC9luW1UusdwEDB6eXEClSyvQ83a9F6rw2F__eXNhmvpW51CpFARU1GlIqGiRlHwGjLVY_sTLKrInE5kEU_9sfHmeg7CIkE205OOYDNXbWRE7sgZCMZAiMLAkAXXo67pRn44OIP7rhNZFLHtzf64MTOG22dRzqGaL_LsAoQk1iSsEWlOFA0nSqLrmkRaqZS2eB_OeXwJjV2UrnYv30GNRv3erOd6L9dwxHnNYROy3oBq8fWd3TDbXCS3JUt_AW1IhzM |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=3H%2C4H%2C5H%2C6H%2C7H-PYRIMIDO%5B4%2C5-B%5D%5B1%2C4%5DOXAZINE-4%2C6-DIONE+DERIVATIVES+AS+TRPA1+INHIBITORS&rft.inventor=BINDER%2C+Florian+Paul+Christian&rft.inventor=FLECK%2C+Martin+Thomas&rft.date=2024-09-19&rft.externalDBID=A9&rft.externalDocID=AU2022258653A9 |