A SYSTEM FOR STORING OR CULTIVATING OF AN ORGAN OR TISSUE MODEL AND USES THEREOF

• Main Authors: ZAMORA, Igor, WSZOLA, Michal, KLAK, Marta, SZCZYGIELSKI, Mateusz, DOBRZANSKI, Tomasz, BERMAN, Andrzej, KUBINKIEWICZ, Dawid
• Format: Patent
• Language: English
• Published: 08.02.2024
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; BEER; BIOCHEMISTRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; ENZYMOLOGY; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; SPIRITS; TRAPPING; VINEGAR; WINE

The invention relates to a system for storing or cultivating of an organ or a tissue model, and to a use thereof. The system is designed for verifying the functioning of a harvested organ or a tissue model and allows for treating it. The system may be used to cultivate organs or tissue models harvested from donors and/or produced using other techniques, such as using 3D and/or 4D bioprinting or electrospinning technology, and comprises: a chamber (2) for the organ or tissue model equipped with means for measuring and adjusting temperature of perfusion fluid in the chamber; a perfusion fluid container (1) equipped with means for measuring and adjusting temperature of the perfusion fluid therein; means (4) for measuring glucose concentration in the perfusion fluid and for dosing glucose into the perfusion fluid; means (3) for measuring pH of the perfusion fluid and for dosing substance for adjusting the pH of the perfusion fluid; means for contactless mixing of the perfusion fluid; and means for measuring and controlling of flow parameters of the perfusion fluid.