Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BT...

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Main Authors QIU, Yubin, TOKSOZ, Engin, HANKS, Shawn Michael, GHOSH, Joy Gispati, MOKER, Nina, BIGELOW, Chad Eric, TWAROG, Michael Zbigniew, HAUBST, Nicole, CHASTAIN, James Edgar, STEFANIDAKIS, Michael, ETEMAD-GILBERTSON, Bijan Alexandre, CARRION, Ana Maria, POOR, Stephen Hendrick, NGUYEN, Andrew Anh, IYER, Ganesh Rajan, RANGASWAMY, Nalini Velamur, CLARK, Kirk Lee
Format Patent
LanguageEnglish
Published 02.02.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.
AbstractList The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.
Author CLARK, Kirk Lee
IYER, Ganesh Rajan
STEFANIDAKIS, Michael
GHOSH, Joy Gispati
BIGELOW, Chad Eric
CHASTAIN, James Edgar
ETEMAD-GILBERTSON, Bijan Alexandre
POOR, Stephen Hendrick
RANGASWAMY, Nalini Velamur
CARRION, Ana Maria
QIU, Yubin
TOKSOZ, Engin
MOKER, Nina
NGUYEN, Andrew Anh
TWAROG, Michael Zbigniew
HAUBST, Nicole
HANKS, Shawn Michael
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– fullname: BIGELOW, Chad Eric
– fullname: TWAROG, Michael Zbigniew
– fullname: HAUBST, Nicole
– fullname: CHASTAIN, James Edgar
– fullname: STEFANIDAKIS, Michael
– fullname: ETEMAD-GILBERTSON, Bijan Alexandre
– fullname: CARRION, Ana Maria
– fullname: POOR, Stephen Hendrick
– fullname: NGUYEN, Andrew Anh
– fullname: IYER, Ganesh Rajan
– fullname: RANGASWAMY, Nalini Velamur
– fullname: CLARK, Kirk Lee
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Snippet The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
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