Alpha-hydroxylated fatty-acid metabolites, medical uses of same and use as biomarkers

Described are fatty acids with one or more unsaturations, having an odd hydrocarbon chain, the fatty acids having the chemical structure of the therapeutically active metabolites of even-chain mono- or polyunsaturated alpha-hydroxylated fatty acids. Also described are compositions comprising said fa...

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Main Authors ESCRIBÁ RUIZ, Pablo Vicente, FERNÁNDEZ GARCÍA, Paula, BETETA GOBEL, Roberto, CABOT BAUZÁ, Juan, ARBONA GONZÁLEZ, Laura, LLADÓ CAÑELLAS, Victoria, ROSSELLÓ CASTILLO, Catalina Ana, BUSQUETS XAUBET, Xavier, PARETS BARRIOS, Sebastià, MILLARES PIZÀ, Marc, RODRÍGUEZ LORCA, Raquel, CANO URREGO, Emilce, TORRES CANALEJO, Manuel
Format Patent
LanguageEnglish
Published 22.09.2022
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Described are fatty acids with one or more unsaturations, having an odd hydrocarbon chain, the fatty acids having the chemical structure of the therapeutically active metabolites of even-chain mono- or polyunsaturated alpha-hydroxylated fatty acids. Also described are compositions comprising said fatty acids, medical uses thereof, and the use thereof as indicators of the efficacy of and/or response to the treatment of a patient with the even-chain mono- or polyunsaturated alpha-hydroxylated fatty acids from which they are derived.
Bibliography:Application Number: AU20210212330