Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use

The present invention relates to combinations comprising a positive allosteric modulator ("PAM") of metabotropic glutamatergic receptor subtype 2 ("mGluR2") or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic 5 recep...

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Main Authors Cid-Nunez, Jose Maria, Klein, Brian D, Ceusters, Marc Andre, Bone, Roger Francis, Twyman, Roy E, White, H. Steven, Van Osselaer, Nancy Eulalie Sylvain, Trabanco-Suárez, Andrés Avelino, Lavreysen, Hilde, Pype, Stefan Maria Christiaan
Format Patent
LanguageEnglish
Published 19.01.2023
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract The present invention relates to combinations comprising a positive allosteric modulator ("PAM") of metabotropic glutamatergic receptor subtype 2 ("mGluR2") or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic 5 receptor subtype 2 compound or a pharmaceutically acceptable salt or a solvate thereof, and a synaptic vesicle protein 2A ("SV2A") ligand.
AbstractList The present invention relates to combinations comprising a positive allosteric modulator ("PAM") of metabotropic glutamatergic receptor subtype 2 ("mGluR2") or a pharmaceutically acceptable salt or a solvate thereof, or an orthosteric agonist of metabotropic glutamatergic 5 receptor subtype 2 compound or a pharmaceutically acceptable salt or a solvate thereof, and a synaptic vesicle protein 2A ("SV2A") ligand.
Author Trabanco-Suárez, Andrés Avelino
Pype, Stefan Maria Christiaan
Van Osselaer, Nancy Eulalie Sylvain
Lavreysen, Hilde
Cid-Nunez, Jose Maria
White, H. Steven
Ceusters, Marc Andre
Klein, Brian D
Bone, Roger Francis
Twyman, Roy E
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– fullname: Bone, Roger Francis
– fullname: Twyman, Roy E
– fullname: White, H. Steven
– fullname: Van Osselaer, Nancy Eulalie Sylvain
– fullname: Trabanco-Suárez, Andrés Avelino
– fullname: Lavreysen, Hilde
– fullname: Pype, Stefan Maria Christiaan
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Snippet The present invention relates to combinations comprising a positive allosteric modulator ("PAM") of metabotropic glutamatergic receptor subtype 2 ("mGluR2") or...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
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