Radiolabelled GRPR-antagonist for use as theragnostic
The present disclosure relates to gastrin-releasing peptide receptor (GRPR) targeting pharmaceuticals and their use in a theragnostic approach for selection and therapy of subjects with GRPR-expressing malignancies. In particular, the present disclosure relates to a pharmaceutical composition of a r...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English |
| Published |
23.05.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present disclosure relates to gastrin-releasing peptide receptor (GRPR) targeting pharmaceuticals and their use in a theragnostic approach for selection and therapy of subjects with GRPR-expressing malignancies. In particular, the present disclosure relates to a pharmaceutical composition of a radiolabeled GRPR-antagonist, for use in treating GRPR-positive tumors in a human subject selected for said treatment, wherein said subject has been selected for the treatment by PET/CT or PET/MRI imaging with a corresponding |
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| AbstractList | The present disclosure relates to gastrin-releasing peptide receptor (GRPR) targeting pharmaceuticals and their use in a theragnostic approach for selection and therapy of subjects with GRPR-expressing malignancies. In particular, the present disclosure relates to a pharmaceutical composition of a radiolabeled GRPR-antagonist, for use in treating GRPR-positive tumors in a human subject selected for said treatment, wherein said subject has been selected for the treatment by PET/CT or PET/MRI imaging with a corresponding |
| Author | CHICCO, Daniela MARIANI, Maurizio F WEGENER, Antje ORLANDI, Francesca |
| Author_xml | – fullname: WEGENER, Antje – fullname: ORLANDI, Francesca – fullname: MARIANI, Maurizio F – fullname: CHICCO, Daniela |
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| RelatedCompanies | NOVARTIS AG |
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| Snippet | The present disclosure relates to gastrin-releasing peptide receptor (GRPR) targeting pharmaceuticals and their use in a theragnostic approach for selection... |
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| Title | Radiolabelled GRPR-antagonist for use as theragnostic |
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