Stable, concentrated radiopharmaceutical composition

The present disclosure relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degrada...

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Main Authors BARBATO, Donato, SACCHETTI, Lorenzo, ORLANDI, Francesca, TEDESCO, Mattia, FUGAZZA, Lorenza, MARIANI, Maurizio F
Format Patent
LanguageEnglish
Published 28.04.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The present disclosure relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.
AbstractList The present disclosure relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.
Author TEDESCO, Mattia
FUGAZZA, Lorenza
MARIANI, Maurizio F
BARBATO, Donato
SACCHETTI, Lorenzo
ORLANDI, Francesca
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– fullname: MARIANI, Maurizio F
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Snippet The present disclosure relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product...
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HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Stable, concentrated radiopharmaceutical composition
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