Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same

Provided herein are formulations, processes, solid forms and methods of use relating to salts of and solid forms comprising free base or salts of (S)-4-(4-(4-(((2-(2,6- dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-l-yl)-3- fluorobenzonitrile.

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Main Authors ARTMAN III, Gerald D, TAVARES-GRECO, Paula A, WU, Wenju, HUANG, Lianfeng, JAIN, Udaykumar, MAN, Hon-Wah, YIN, Zhiwei, TSOU, Nancy Nienhua, FERRETTI, Antonio C
Format Patent
LanguageEnglish
Published 29.07.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided herein are formulations, processes, solid forms and methods of use relating to salts of and solid forms comprising free base or salts of (S)-4-(4-(4-(((2-(2,6- dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-l-yl)-3- fluorobenzonitrile.
AbstractList Provided herein are formulations, processes, solid forms and methods of use relating to salts of and solid forms comprising free base or salts of (S)-4-(4-(4-(((2-(2,6- dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-l-yl)-3- fluorobenzonitrile.
Author TSOU, Nancy Nienhua
WU, Wenju
YIN, Zhiwei
HUANG, Lianfeng
JAIN, Udaykumar
TAVARES-GRECO, Paula A
ARTMAN III, Gerald D
FERRETTI, Antonio C
MAN, Hon-Wah
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– fullname: JAIN, Udaykumar
– fullname: MAN, Hon-Wah
– fullname: YIN, Zhiwei
– fullname: TSOU, Nancy Nienhua
– fullname: FERRETTI, Antonio C
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Snippet Provided herein are formulations, processes, solid forms and methods of use relating to salts of and solid forms comprising free base or salts of...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same
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