Assessment of cellular signaling pathway activity using linear combination(s) of target gene expressions

The present application mainly relates to specific methods for inferring activity of a cellular signaling pathway in tissue and/or cells of a medical subject based at least on expression levels of one or more target gene(s) of the cellular signaling pathway measured in an extracted sample of the tis...

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Bibliographic Details
Main Authors Wilhelmus, Franciscus Johannes Verhaegh, Van Ooijen, Hendrick Jan, Van de Wiel, Paul Arnold
Format Patent
LanguageEnglish
Published 14.05.2020
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Summary:The present application mainly relates to specific methods for inferring activity of a cellular signaling pathway in tissue and/or cells of a medical subject based at least on expression levels of one or more target gene(s) of the cellular signaling pathway measured in an extracted sample of the tissue and/or cells of the medical subject, an apparatus comprising a digital compressor configured to perform such methods and a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such methods.
Bibliography:Application Number: AU20200202706