Process for the preparation of a cyclic dinucleotide

The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.

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Main Authors TREITLER, Daniel S, SEZEN EDMONDS, Melda, PURDUM, Geoffrey Eugene, YU, Miao, SCHMIDT, Michael Anthony, FREITAG, Adam Joseph, ROGERS, Amanda J, HANG, Chao, ZHENG, Bin, YUAN, Changxia, COHEN, Benjamin M, GUO, Siwei, ZHU, Jason J
Format Patent
LanguageEnglish
Published 22.07.2021
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Abstract The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.
AbstractList The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.
Author ROGERS, Amanda J
SEZEN EDMONDS, Melda
ZHU, Jason J
ZHENG, Bin
COHEN, Benjamin M
YU, Miao
HANG, Chao
PURDUM, Geoffrey Eugene
TREITLER, Daniel S
GUO, Siwei
YUAN, Changxia
SCHMIDT, Michael Anthony
FREITAG, Adam Joseph
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– fullname: SCHMIDT, Michael Anthony
– fullname: FREITAG, Adam Joseph
– fullname: ROGERS, Amanda J
– fullname: HANG, Chao
– fullname: ZHENG, Bin
– fullname: YUAN, Changxia
– fullname: COHEN, Benjamin M
– fullname: GUO, Siwei
– fullname: ZHU, Jason J
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Snippet The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following...
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SubjectTerms CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
Title Process for the preparation of a cyclic dinucleotide
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