Compounds for the treatment of seizures and other central nervous system disorders and conditions

• Main Authors: Estey, Paula J, Nagireddy, Jaipal R, Robinson, Gary L.W.G, Araujo, Joseph A, Higgins, Guy A, Milgram, Norton W, Andrews, John S, Annedi, Subhash C
• Format: Patent
• Language: English
• Published: 11.03.2021
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present application relates to novel compounds comprising a moiety that leads to the metabolic production of ketones bonded to a ketone- potentiated anti-epileptic drug, compositions comprising these compounds, and their use, for example for the treatment of epilepsy, and other CNS diseases, dis...