Compounds for the treatment of seizures and other central nervous system disorders and conditions

The present application relates to novel compounds comprising a moiety that leads to the metabolic production of ketones bonded to a ketone- potentiated anti-epileptic drug, compositions comprising these compounds, and their use, for example for the treatment of epilepsy, and other CNS diseases, dis...

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Bibliographic Details
Main Authors Estey, Paula J, Nagireddy, Jaipal R, Robinson, Gary L.W.G, Araujo, Joseph A, Higgins, Guy A, Milgram, Norton W, Andrews, John S, Annedi, Subhash C
Format Patent
LanguageEnglish
Published 11.03.2021
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present application relates to novel compounds comprising a moiety that leads to the metabolic production of ketones bonded to a ketone- potentiated anti-epileptic drug, compositions comprising these compounds, and their use, for example for the treatment of epilepsy, and other CNS diseases, disorders or conditions. In particular, the present application includes compounds of Formula I, and compositions and uses thereof:
Bibliography:Application Number: AU20190268209