Use Of Derivatives With C-O-P Bonds In Patients With Kidney Failure

• Main Authors: SALCEDO ROCA, Carolina, JOUBERT, Pieter H, PERELLO BESTARD, Joan, FERRER REYNES, Miquel David, ISERN AMENGUAL, Bernat
• Format: Patent
• Language: English
• Published: 08.04.2021
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Use of a derivative containing C-O-P bonds in a controlled release form to treat patients with kidney failure. Moreover, it comprises the use of said derivatives together with other active substances, which particularly may be selected from a list comprising a calcimimetic, vitamin, phosphate binder, thiosulfate, bisphosphonate, pyrophosphate, citrate, diuretic, antihypertensive and anticholesteraemic agent. * 25 mg HAP U 75 mg HAP 5 g. A 130 mg HAP Y 300 mg HAP IP6 adsorbed (mg/g HAP) 0.1 0.3 1 3 10 Figure 1 IP6 adsorbed (mg/g HAP) 3 0 100 20o 300 400 500 Tiempo (min) Time (min) Figure 2