Methods for the preparation of ribosides

• Main Authors: Campagna, Silvio, Waltman, Andrew W, Heumann, Lars V, Lew, Willard, Milburn, Robert Ronald, Rueden, Erick, Ross, Bruce, Tadeus, Clarissa, Wolfe, Lydia, Scott, Robert William, Axt, Steven Donald, Gao, Detian, Frick, Morin Mae, Doerffler, Edward, Chtchemelinine, Andrei, Wang, Xianghong, Brak, Katrien, Neville, Sean Timothy, Yu, Chia-Yun, Siegel, Dustin, Hoang, Brittanie, Badalov, Pavel Robertovich, Vieira, Tiago, Whitcomb, Mark Charles, Stevens, Andrew C
• Format: Patent
• Language: English
• Published: 14.03.2019
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SUGARS

Provided are methods of preparing compounds and pharmaceutical compositions for treating Filoviridae virus infections The compounds, compositions, and methods provided are particularly useful for the treatment of Marburg virus, Ebola virus and Cueva virus infections.