Anti-Leukocyte Adhesion For The Mitigation Of Potential Adverse Events Caused By CD3-Specific Binding Domains

• Main Authors: Nagorsen, Dirk, Kufer, Peter, Hoffmann, Patrick, Klinger, Matthias, Scheele, Juergen, Zugmaier, Gerhard, Naegele, Virginie, Dopfer, Elaine-Pashupati
• Format: Patent
• Language: English
• Published: 13.08.2020
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Abstract The present invention relates in essence to a compound which decreases or inhibits the binding of mammalian T-cells to mammalian endothelial cells for use in a method of prophylaxis and/or amelioration and/or treatment of clinical adverse events caused by therapy which comprises re-directin...