Immunoproteasome inhibitors
Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also...
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| Main Authors | , , , |
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| Format | Patent |
| Language | English |
| Published |
27.04.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds. |
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| AbstractList | Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds. |
| Author | GOLDSTEIN, David Michael OWENS, Timothy Duncan LOU, Yan BRAMELD, Kenneth Albert |
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| RelatedCompanies | PRINCIPIA BIOPHARMA INC |
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| Snippet | Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and... |
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| Title | Immunoproteasome inhibitors |
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