Compositions for facilitating membrane fusion and uses thereof

• Main Authors: Von Maltzahn, Geoffrey A, Rubens, Jacob Rosenblum, Milwid, John Miles, Zhang, Bo, Mee, Michael Travis, Gibson, Molly Krisann, Mahdaviani, Kiana, Putiri, Tamar Rose, Dobbin, Matthew Milnes, Gordon, Neal Francis, Stebbins, Nathan Wilson, Trudeau, Kyle Marvin, Hartley, Brigham Jay
• Format: Patent
• Language: English
• Published: 07.11.2024
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

In some aspects, fusosome compositions and methods are described herein that comprise membrane enclosed preparations, comprising a fusogen. In some embodiments, the fusosome can the target cell, thereby delivering complex biologic agents to the target cell cytoplasm.