Pyrazine derivatives useful as inhibitors of ATR kinase

• Main Authors: DURRANT, Steven, REAPER, Philip Michael, MACCORMICK, Somhairle, PINDER, Joanne, KAY, David, VIRANI, Anisa Nizarali, YOUNG, Stephen, KNEGTEL, Ronald, O'DONNELL, Michael, MORTIMORE, Michael, CHARRIER, Jean-Damien, RUTHERFORD, Alistair
• Format: Patent
• Language: English
• Published: 18.06.2020
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Abstract The present invention relates to pyrazine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; me thods of treating of various diseases, disorders, and conditions using the co...