Compositions with a rheological modifier to reduce dissolution variability

• Main Authors: FU, Roger, ZAMLOOT, Michael S, SHANKER, Ravi M, YUM, Su Il, CHAO, Wendy, SU, Huey-Ching, BRATIN, Karl
• Format: Patent
• Language: English
• Published: 25.01.2018
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time de...